London Irish have made one change for tomorrow's Aviva Premiership trip to Exeter Chiefs (kick-off 3pm).
Italian international Luke McLean replaces Fergus Mulchrone at inside centre, the former Sale man ruled out with a hamstring injury.
McLean, who has played 89 times for the Azzurri, partners Canadian international Ciaran Hearn at the heart of Irish's backline as Nick Kennedy's men look to build on last weekend's impressive bonus point triumph over Harlequins at Twickenham.
Notching up 24 of the Exiles' 39 points in the season opener, Tommy Bell starts at full-back, while Alex Lewington and Topsy Ojo retain their place on either wing.
James Marshall, the catalyst for Irish's opening try of the campaign, gets the nod alongside scrum-half Scott Steele.
Meanwhile, Danny Hobbs-Awoyemi, skipper David Paice and Petrus Du Plessis all pack down in the front row, while Franco van der Merwe and Sebastian De Chaves provide composure in the engine room.
The axes of Irish's inspiring defensive display against Quins, Mike Coman and Blair Cowan start at blindside and openside flanker respectively.
Ofisa Treviranus, a try scorer during the Quins win, pulls on the No 8 jersey.
Exiles' boss Kennedy is relishing the challenge of going toe to toe with the reigning Aviva Premiership champions.
“We're really looking forward to the trip to Exeter,” said Kennedy.
“Exeter are a quality team with threats right across the field, so we'll have to be at our very best in every department.
“They are a team that we have a great deal of respect for and it doesn’t get any bigger than playing the Premiership champions at Sandy Park.”
London Irish: 15 Tommy Bell, 14 Alex Lewington, 13 Ciaran Hearn, 12 Luke McLean, 11 Topsy Ojo, 10 James Marshall, 9 Scott Steele, 1 Danny Hobbs-Awoyemi, 2 David Paice (c), 3 Petrus Du Plessis, 4 Franco van der Merwe, 5 Sebastian De Chaves, 6 Mike Coman, 7 Blair Cowan, 8 Ofisa Treviranus
Replacements: 16 Dave Porecki, 17 Gordon Reid, 18 Ben Franks, 19 Josh McNally, 20 Conor Gilsenan, 21 Brendan McKibbin, 22 Greig Tonks, 23 Aseli Tikoirotuma
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