Jerry Sexton insists the squad will use the disappointment of Saturday's defeat to Jersey as motivation to get things back on track this week.
"We probably didn't show up and play our best rugby on Saturday, so we are itching to get out there and put it right this week," said Sexton.
Having seen first-hand what Jersey can do in previous matches this season, the imposing lock is aware of the threat they bring.
"Jersey are a big physical side, they are well coached and they make few mistakes," he added.
"The boys know they need to front up and win collisions or we will struggle against them."
After suffering their first league defeat of the season, Sexton says it is still a game by game mentality amongst the squad.
"It's always game by game, we are performance driven and we know if we do the basics well then results will take care of themselves," he said.
Sexton joined from Exeter Chiefs last season and the 24 year old says he is happy with his position in the squad.
"I set a few goals for myself at the start of the season around game time and consistency," he added.
"I'm grateful for my game time so far this year and I just want to take my opportunity when I get it."
Irish return to the Madejski this Saturday for the British & Irish Cup Semi-final, kick-off 2pm, and Sexton says that the fans support will be crucial.
"The fans have been brilliant this year and we've heard them cheering us on all over the country and at home especially," he said.
"When you're tired or your back is against the wall it helps you so much and all of us in the squad are grateful for the support we receive. We want to do everyone proud on Saturday."
London Irish's next home game is the British & Irish Cup Semi-final against Jersey Reds at 2pm this Sunday 2 April followed by the last regular home league game against Rotherham Titans at 3pm on 8 April. Tickets are available from 0118 968 1016 or go to www.lidirect.co.uk to purchase online.