Shane Geraghty moves back to fly half with James O’Connor moving to the inside centre position. John Yapp starts at loosehead prop and Ian Gough and Mike Mayhew are named as replacements.
John Yapp, David Paice and Jamie Hagan make up the front row with George Skivington and Nic Rouse in the second row. Kieran Low, Blair Cowan and Ofisa Treviranus are named in the back row.
Darren Allinson and Shane Geraghty will start at half back with James O’Connor and Eamonn Sheridan in the centre. Marland Yarde, Alex Lewington and Topsy Ojo make up the back three.
London Irish Director of Rugby, Brian Smith said: “We want to finish this block of Premiership games well and go to Exeter and put in the type of performance that has seen us win away at Saracens and Wasps. Exeter are similar to us in the fact that they will fight for everything, however we have prepared well this week and will go to Sandy Park with a winning intent.”
London Irish team to face Exeter Chiefs:
15. Topsy Ojo *; 14. Alex Lewington; 13.Eamonn Sheridan; 12. James O’Connor*; 11. Marland Yarde*; 10. Shane Geraghty*; 9. Darren Allinson; 1. John Yapp*; 2. David Paice*; 3. Jamie Hagan*; 4. George Skivington (Captain); 5. Nic Rouse; 6. Kieran Low*; 7. Blair Cowan; 8. Ofisa Treviranus*
Replacements: 16. Mike Mayhew; 17. Matt Parr; 18. Leo Halavatau; 19. Jebb Sinclair*; 20. Ian Gough*; 21. Gerard Ellis; 22. Ian Humphreys; 23. Ed Hoadley