Mont-de-Marsan will be the first visitors to Madejski Stadium on Saturday 20th October before back to back fixtures against fellow Premiership side Gloucester Rugby.
The West Country outfit will visit Reading on Saturday 8th December and a week later Brian Smith's side will make the trip to Kingsholm for the return match.
The Exiles will again travel to the south of France in Round 5 to face Mont-de-Marsan before finishing the group stages off against Bordeaux-Begles at Madejski Stadium.
Amlin Challenge Cup Fixtures
Saturday 13th October Bordeaux-Begles vs. London Irish KO 9pm
Saturday 20th October London Irish vs. Mont-de-Marsan KO 3pm
Saturday 8th December London Irish vs. Gloucester KO 3pm
Saturday 15th December Gloucester vs. London Irish KO 3pm
10th/11th/12th/13th January Mont-de-Marsan vs. London Irish KO TBC
17th/18th/19th/20th January London Irish vs. Bordeaux-Begles KO TBC
For a full list of London Irish fixtures click here.
You can come to all sixteen London Irish home fixtures, plus the London Double Header away game, from just £14 per game with a London Irish Season Ticket - and that includes a free Under 16! For more information on season tickets, click here or call 0844 249 1871.
Show your "Exile-Style" and wear it with pride!