Matt Parr, Mike Mayhew and Jamie Hagan will again start in the front row with Ben Toolis and his twin brother Alex, who also joins on a short term loan from Edinburgh, partnering in the second row. Declan Danaher and Bryn Evans will join Low in the back row.
The backline consists of Darren Allinson at scrum half and Shane Geraghty at fly half. Setaimata Sa and Guy Armitage form the centre partnership with Andrew Fenby, Tom Fowlie and Alex Lewington in the back three.
Brian Smith, Exiles Director of Rugby said: “We have made a couple of changes to the squad from last week to freshen things up a little, but on the whole, several of the boys that played last week have a second chance to impress against a good Northampton side.”
London Irish team to face Northampton Saints
15. Alex Lewington; 14.Tom Fowlie; 13. Guy Armitage; 12. Setaimata Sa*; 11. Andrew Fenby; 10. Shane Geraghty (Captain)*; 9. Darren Allinson; 1. Matt Parr; 2. Mike Mayhew; 3. Jamie Hagan*; 4. Alex Toolis; 5. Ben Toolis; 6. Declan Danaher; 7. Bryn Evans*; 8. Kieran Low
Replacements: 16. Jimmy Stevens; 17 Johnny Harris; 18. Leo Halavatau; 19.Ben Lonergan; 20. Danny Kenny; 21. Fergus Mulchrone; 22. Myles Dorrian; 23. Tom Bliss