Bob Casey has recovered from injury and will join Nick Kennedy in the second row to make his 221st appearance for the club. Paul Hodgson comes in at scrum half having recovered from his head injury in place of Darren Allinson. Steffon Armitage returns at openside flanker with Jamie Gibson moving to the blindside flank. Topsy Ojo and Tom Homer switch to the wing and full back respectively. Ryan Lamb has recovered from flu and is named on the bench.
London Irish Head Coach, Toby Booth said: “It is always enjoyable to play in a local derby with Harlequins, they are always hard fought and competitive games. The squad is focused on the job in hand and determined to come away from the game with the right result.”
London Irish team to face Harlequins:
15. Tom Homer; 14. Topsy Ojo*; 13. Seilala Mapusua*; 12. Dan Bowden; 11. Adam Thompstone; 10. Chris Malone; 9. Paul Hodgson*; 1. Clarke Dermody (captain)*; 2. James Buckland; 3. Faan Rautenbach*; 4. Nick Kennedy*; 5. Bob Casey*; 6. Jamie Gibson; 7. Steffon Armitage*; 8. George Stowers*
Replacements: 16. Rob Herring; 17. Max Lahiff; 18. Paulica Ion*; 19. Kieran Roche; 20. Richard Thorpe; 21. Jonathan Joseph; 22. Ryan Lamb; 23. Darren Allinson
* Denotes international
Head Coach: Toby Booth; Attack Coach: Mike Catt; Defence Coach: Dave Ellis